ࡱ > K M J q` @H bjbjqPqP .L : : T T T T T T T h
4 h C < < < < < < < < $ 3 h ! T < < < < < T T < < <
T < T < < T T < 0 t7vD
F " 0 C " T < < < < < < <
< < < C < < < 2 !. .
8><0 ;55 G0AB> 2AB@5G0NI0OAO 4>1@>:0G5AB25==0O >?CE>;L C 65=I8=. 0: 8725AB=>, >A=>2=K< 4>< ;5G5=8O <K AB05BAO E8@C@38G5A:>5 2. 0728B85 A>2@5;>389 ?@825;> : B> C 8 9 87 1 0 65=I8= ?@>872>4OBAO @048:0;L=K5 >?5@0F88 =0 <0B:5 [ 7 ] . 0728B85 D0@;>388 @0AH8@O5B 2>76=>AB8 <548:07=>3> ;5G5=8O <K 2@52 70A;C68205B >A>1>3> 2=8<0=8O ?@5?0@0B =, =0E>4OI89 25AL:>5 ?@8<5=5=85 4;O <548:07=>3> ?@5@K20=8O 15@5AB8 [ 1 , 1 0 ] . A>1K9 8=B5@5A ?@54AB02;O5B 2>76=>ABL 8A?>;L7>20=85 40==>3> ?@5?0@0B0 A F5;LN B>@65=8O @>AB0 <K MB>BK O28;0AL 87CG5=85 :;8=8G5A:>9 MDD5:B82=>AB8 ?@5?0@0B0 = C 1>;L=KE A 9 F5=:0 C@>2=O ?@>4C:F88 @O40 ?@>2>A?0;8B5;L=KE F8B>:8=>2 4> 8 ?>A;5 ;5G5=8O ?@5?0@0B>9 :0B53>@88 1>;L=KE.
0B5@80;K 8 4K. >1A;54>20=85 1K;8 2:;NG5=K 2 0 ?0F85=B>: 2 2>7@0AB5 >B 3 2 4> 4 5 ;5B, A 9 >B25BAB2CNI59 ?> 25;8G8=5 6 1 0 =545;L=>9 15@5AB8 A 8=B5@AB8F80;L=>9 8 AC1A5@>7=>9 ;>:0;870F859 7=KE C7;>2. 5@8>4 =01;N45=8O A AB0=>2:8 4803=>70 <K 1A;54>20==KE 65=I8= >B 1 4> 5 ;5B. 0@O4C A >1I8;>38G5A:81A;54>20=852>48;>AL C;LB@072C:>2>5 A:0=8@>20=85. ;O >?@545;5=8O >1J5<0 2 >?CE>;8 8A?>;L7>20;0AL D>@<C;0 V ( c F5AA>2 M=4> ;5G5=8O ?@>872>48;8 38AB5@>A:>?8N, ;5G51=>- 4803=>AB8G5A:>5 2KA:01;820=85 A;54CNI8;>38G5A:820=85;CG5==>3> A;5 ?@>2545==>3> :C@A0 :>=A5@20B82=>9 B5@0?88 >F5=820;8 1I55 A>AB>O=85 8 A0GC2AB285 ?0F85=B:8, 48=0<8:C :;8=8G5A:8E A82 <K 1J5= =07=0G0;AO A> 2 4;O 3> F8:;0 5654=52=> =5?@5@K2=> 2 4>75 5 0 <3. C@A ?@85B 3 4> 6 1A;54>20==KE 65=I8= 1 2 ?@8=8<0;8 ?@5?0@0B 2 B5G5=85 3 : 6 A;5 ?5@2>3> : =0ABC?0;0 ?A524>?0C70 8 ?>A;5 >:>=G0=8O ;5G5=8O AAB0=>28;0AL G5@57 3 6 =545;L. A;54CNI59 B01;8F5 ?@54AB02;5=K 40==K5 >1 C1J5?CE>;8 ?>4 2;8O=852>489 B5@0?88.
"01;8F0 1
7<5=5=8O @072 : A 9 ?>4 2;8O=85< =0
'8A;> ?0F85=B>: !@>:8 >1A;54>20=8O, <5A. 1J5< 4=>: >1A;54C59 3@C??K G5@57 3 B =0G0;0 ;5G5=85 >1J5< <0B:8 C1J5=0G0;L=>9 25;8G8=K; C 8 ?0F85=B>: ?@>4>;602H8E ?@85< ?@5?0@0B0 2 B5G5=85 6 1J5 A@02=5=8N A 8AE>4=K<8 40==KA;54CNI55 C;LB@072C:>2>5 8AA;54>20=85 1K;> 2K?>;=5=> 9 ?0F85=B:0< G5@57 6 A;5 >B;L=K;L=KE 1K; ?>;CG5= 2@5 40==K2>3> 8AA;54>20=8O B>;I8=0 M=4>H @H hQ hQ mH sH hQ hQ OJ QJ mH sH hQ B*OJ QJ ph f U hQ 5hQ 5OJ QJ hQ 5B*OJ QJ aJ ph f hQ 5OJ QJ aJ hQ OJ QJ mH sH hQ 5OJ QJ \ hQ OJ QJ -
6 * . B ( d $dh $If a$gdQ
$dh a$gdQ $a$gdQ
$dh a$gdQ
$dh a$gdQ gdQ
@H d f ~ o o o $dh $If a$gdQ kd $$If l F
$ v v w 0 6 4
l a 8 ~ o o o $dh $If a$gdQ kd $$If l F
$ v v w 0 6 4
l a 8 : ^ | ~ o o o $dh $If a$gdQ kd: $$If l F
$ v v w 0 6 4
l a 4 9 : <; | (? H@ 8A ^B ~ s s s s s s s s s s s s
$dh a$gdQ kd $$If l F
$ v v w 0 6 4
l a
>A;5 ;5G5=8O =>< 2 B5G5=85 6 ;510;0AL 2 ?@545;0E 0 , 0 , 9 AB0 @0728B8O ?>1>G=KE @50:F89 ?@8 ;5G51=>7459AB288 =0 C ?0F85=B>: A 9 <0B:8 2 B5G5=85 6 3> ?@851>G=KE MDD5:B>2 B>;L:> 2 1 0 % A;CG052 >BA;>6=5=89 :0: ?@8102:0 B5:8, B>H=>B0, 3>;>2=O 1>;L, :@>2>B5G5=8O ?@>@K20 =02;5=>. !;54C5B C:070BL =0 E>@>HCN ?5@5=>A8ABL ?@5?0@0B0. BACBAB285 MDD5:B0 >B ;5G5=8O C 3 ?0F85=B>: 2 @5?@>4C:B82=>7@0AB5 ?>A;C68;> >A=>20=85?5@0B82=>3> ;5G5=8O.
0: ?>:070;8 ?>;CG5==K5 40==K5, 8A?>;L7>20=85 =0 ?@82>48B : B>@65=8N 8 ACI5AB25==>?CE>;8. @8G5< C1J5?CE>;8 1K;> 1>;55 2K@065=>, ?> A@02=5=8N A 4@C38<8 2840@=0;L=>3> 2>7459AB28O ?@8 4C:B82=>3> 2>7@0AB0. @5645 2A53>, MB> >B=>A8BAO : 4>AB0B>G=> H8@>:>, ?@8<5=O5<K< ?@8 <5 @MB8AB5@>=C, 40=07>;C 8 35AB@8=>=C [ 2 , 3 , 1 1 ] . -B>B MDD5:B =0 =081>;55 70< ( 6 <5A) ?@83> ?@5?0@0B0. !;54C5B >B;>68B5;L=>5 2;8O=85 =0 =0 M=4>B>@K9 C >1A;54>20==KE 65=I8= A>>B25BAB2>20; @0==59 AB0488 D07K ?@>;8D5@0F88 [ 9 ] .
8B5@0BC@0.
1 . 10H8= . . , C7=5F>20 ". . , 5B@>AO= . !. 8 4@. @5@K20=85 15@5AB8 2 B@8< <0 2>4AB2> ?> M=4>:@8==>9 38=5:>;>388/ >4 @54. . . 8E;O52>9. . : 548F8=A:>5 8=D>@==>5 035=AB2>, 1 9 9 7 . !. 4 2 4 4 8 6 .
3 . 8E;O520 . . C:>2>4AB2> ?> 4803=>AB8:5 8 ;5G5=8N ;59><K @ . . >;5:C;O@=K5 <5E0=87F5AA>2. . : 74- 2> 82@54E>4K : 87CG5=8N ?0B>35=570 1>;57=59 / / 5AB=8: 1 9 9 9 . !9 . !. 2 2 - 2 5 .
6 . 5B@>AO= . !. , CA0:>20 . !, 0:0F0@8O . . @8<5=5=85 =0 2 0CH5@A:> 38=5:>;>38G5A:>9 ?@0:B8:5 / / :CH. 8 38=. 2 0 0 0 . !1 . !. 2 0 - 2 5 .
7 . !028F:89 . . , !028F:89 . . 8><0 1;535=570 8 ?0B>35=5B8G5A:>9 B5@0?88) . ! 1. : - ! 1 , 2 0 0 0 .
8 . !84>@>20 . !. 8><0 2@51;5;>388, ?0B>35=570, 4803=>AB8:8 8 ;5G5=8O) . . : 548F8=A:>5 8=D>@==>5 035=AB2>, 2 0 0 2 .
9 . !B@C:>2 . . 528B0A !. . #;LB@072C:>20O 4803=>AB8:0 2 0:CH5@AB25, 38=5:>;>388 8 ?5@8=0B>;>388. . , 1 9 9 2 .
1 0 . "0?8;LA:0O . . , 094C:>2 !. . ?KB ?@>2545=8O <548:07=>3> ?@5@K20=8O 15@5AB8 ?@5?0@0B>:, A52@51;5<K. !1. 9 :>=D. ! 1. , 2 0 0 1 . !. 7 2
1 1 . C o u t i n h o E . , B o u l a n g e r G . , C o n c a l v e s M . R e g r e s s i o n o f u t e r i n e l e i o m y m a s a f t e r t r e a t m e n t w i t h g e s t r i n o n e , a n a n t i a s t r o g e n , a n t i p r o g e s t e r o e / / A m e r . J . O b s t e t . G y n e c o l 1 9 8 6 . V o l . 1 5 5 - !4 . !. 7 6 1 7 6 7 .
1 2 . L a s e k W . , F e l e s z k o W , G o l a b J , S t o r l o s a T . A n t i t u m o r e f f e c t s o f t h e c o m b i n a t i o n i m m u n o t h e r a p y w i t h i n t e r l e u k i n 1 2 a n d t u m o r n e c r o s i s f a c t o r a l p h a i n m i c e / / C a n c e r I m m u n o l I m m u n o t h e . - 1 9 9 7 . - V o l . 4 5 . - P . 1 0 0 - 8 .
^B H @H
$dh a$gdQ , 1h . A!"R#n$n% $$If !v h5 v 5v 5w #v v #vw :V l 0 6 5 v 5w 4 $$If !v h5 v 5v 5w #v v #vw :V l 0 6 5 v 5w 4 $$If !v h5 v 5v 5w #v v #vw :V l 0 6 5 v 5w 4 $$If !v h5 v 5v 5w #v v #vw :V l 0 6 5 v 5w 4 B ` B Q 1KG=K9 CJ _HaJ mHsHtHP ` P Q 03>;>2>: 1 $$$dh @& a$ 5aJ B A@ B A=>2=>9 H@8DB 0170F0 X i@ X 1KG=0O B01;8F0 4
l 4 a . k@ .
5B A?8A:0 R B` R Q A=>2=>9 B5:AB $dh a$ 5CJ \aJ L f
2
3
F
U
g
h
z
] d S [ ] 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2
3
g
h
K 00 @ 0 K 00 @ 0 K 00 @ 0 K 00 @ 0
0 0 @H d 8 ^B @H % @H f p D O s ~ " # ~ Y
e
: F h u w & 2 , 3 7 ; ? B ` h
6 ? M \ u | e m s | B O a k 9 A F O T ] w
# ( , 4 8 A (
1
L W 3 3
C
Q
2
3
F
U
g
h
z
@ ) 0 U n k n o w n G z T i m e s N e w R o m a n 5 S y m b o l 3& z A r i a l 9 G a r a m o n d " q h ) - ) - $ 24 2q HP ) ? Q 2 e ! " ' + " # ) #" !" " $ !" ;048<8@ ;048<8@ Oh +'0 ( 4 @ P d p
h Normal 1 Microsoft Office Word @ @ 4kD@ 4kD ) ՜. +,0 T h p
2 Vlad - f
! " # $ % & ( ) * + , - . 0 1 2 3 4 5 6 7 8 9 ; ? @ A C D E F G H I L R o o t E n t r y F AvDN D a t a
' 1 T a b l e / W o r d D o c u m e n t .L S u m m a r y I n f o r m a t i o n ( : D o c u m e n t S u m m a r y I n f o r m a t i o n 8 B C o m p O b j q
F Microsoft Office Word
MSWordDoc Word.Document.8 9q
-
restart
intex
-
2113
3d
kaasi
-
i`m o.k./